Headline stats

>1.3 billion children vaccinated through routine programmes, 2000–2025 – more than 73 million in 2025 alone
>2.4 billion vaccinations through preventive vaccination campaigns, 2000–2025

>23 million future deaths averted, 2000–2025 (including 2.2m in 2025 alone – the most lives saved in a single year)
>US$ 308 billion in economic benefits generated in the countries we support, 2000–2025

779 vaccine introductions and preventive vaccination campaigns, 2000–2025
US$ 2.2 billion in co-financing contributions from Gavi‑supported countries since 2008 – and a high of US$ 301m in 2025 alone

US$ 54 for US$ 1 spent

A study covering 73 Gavi-supported countries shows that, for every US$ 1 spent on immunisation in the 2021–2030 period, US$ 21 are saved in health care costs, lost wages and lost productivity due to illness and death. When considering the value people place on lives saved by vaccines – which is likely to include the value of costs averted plus the broader societal value of lives saved and people living longer and healthier lives – the return on investment is estimated to be US$ 54 per US$ 1 spent.

Sim S.Y., Watts E., Constenla D., Brenzel L., Patenaude B.N. Return On Investment From Immunization Against 10 Pathogens In 94 Low- And Middle-Income Countries, 2011–30. Health Affairs, 2020

Strategic goals

Our mission – to save lives and protect people’s health by increasing equitable and sustainable use of vaccines – is supported by four strategic goals.

The vaccine goal

Introduce and scale up vaccines

65%

The 57 Gavi-supported countries increased breadth of protection with vaccines in the Gavi portfolio to 65%, up 2 percentage points from 2024.

84

84 Gavi-supported vaccine introductions and preventive campaigns took place in 2025 – in addition to 50 outbreak response vaccination campaigns supported by Gavi.

>35 million

>35 million girls fully immunised against HPV with Gavi support in 2025 alone – the highest number yet.

19

countries accessed cholera, Ebola, meningococcal and yellow fever vaccines through Gavisupported emergency stockpiles a total of 63 times in 2025.

The equity goal

Strengthen health systems to increase equity in immunisation

82%

In 2025, Gavi-supported countries increased DTP3 coverage to 82% (compared to the 85% global average).

>73 million

>73 million children were reached with Gavi-supported routine vaccines in 2025 – more than in any year previously.

>50

>50 countries have installed more than 71,000 cold chain equipment (CCE) units procured by UNICEF Supply Division through Gavi’s CCEOP – more than 2,700 in 2025 alone.

82%

In 2025, Gavi-supported countries increased DTP3 coverage to 82% (compared to the 85% global average).

The sustainability goal

Improve sustainability of immunisation programmes

US$ 2.2 billion

In the face of fiscal challenges, climate change, conflict and instability, most Gavi-supported countries maintained or increased domestic resources for co-financing of Gavi-supported vaccines in 2025, bringing to US$ 2.2 billion their total contribution since the introduction of the co‑financing policy in 2008. 

US$ 301 million

US$ 301 million was contributed by countries towards the cofinancing of Gavisupported vaccines in 2025 – the highest amount yet and a testament to country ownership and the long-term financial sustainability of Gavi-supported vaccines.

56

56 vaccine programmes originally introduced with Gavi funding are self-financed by countries as of 2025, up from 40 in 2018.

100%

100% of countries fully met their 2025 co-financing obligation – except six waivers for humanitarian crises.

The healthy markets goal

Ensure healthy markets for vaccines and related products

19

Through Gavi’s market shaping efforts, the number of manufacturers supplying prequalified Gavi-supported vaccines reached 19 in 2025 (with nearly half based in low- and middleincome countries) – compared with 5 in 2001.

11

markets for vaccines and immunisation products exhibited acceptable levels of healthy market dynamics in 2025, exceeding the Gavi 5.0/5.1 target.

14

14 innovative products of relevance to lower-income countries were within the pipeline of commercial-scale manufacturers in 2025, continuing to surpass the cumulative target for Gavi 5.0/5.1.

500,000

500,000 mpox vaccine doses secured within a month of the WHO emergency declaration.

Last updated: 12 Oct 2026