Latest articles about cholera       Routine vaccines: Cholera

Gavi’s impact

Approximately 70 million doses of oral cholera vaccine distributed from the Global OCV Stockpile

PREVENTING AND RESPONDING TO OUTBREAKS

To support emergency response, humanitarian crises and preventive vaccination in countries with endemic cholera, Gavi has supported the Global Oral Cholera Vaccine (OCV) Stockpile since 2014. Since then, the Stockpile has been accessed 87 times by 22 countries, with approximately 70 million doses shipped as of end 2020.

The Stockpile comprises an emergency component managed by the International Coordinating Group (ICG) on Vaccine Provision – the same mechanism used for emergency Ebola, meningococcal and yellow fever vaccine stockpiles – and a non-emergency reserve, which is used to vaccinate preventively in cholera hotspots. The ICG includes four Alliance partners: the International Federation of Red Cross and Red Crescent Societies (IFRC), Médecins Sans Frontières (MSF), UNICEF and WHO.

REDUCING CHOLERA DEATHS BY 90% BY 2030

The momentum for action against cholera greatly accelerated in 2018, with the World Health Assembly’s adoption of a resolution on cholera prevention and control, aimed at reducing cholera deaths by 90% by 2030. Increasingly, affected countries are developing national multisectoral cholera control plans, including preventive OCV use to reduce the burden of cholera, prevent outbreaks and protect people while scaling up long-term investments in improved water, sanitation and hygiene (WASH).

With its aim to reach unvaccinated children, the Gavi 5.0 strategic period (2021–2025) is an opportunity to pursue synergies with Ending Cholera—A Global Roadmap to 2030 to ensure communities facing multiple deprivations have comprehensive access to health and other services, including safe water, sanitation and hygiene. Cholera control activities can prevent other diarrhoeal diseases; and cholera vaccination campaigns can be leveraged to reach these communities with other essential services.

 

Reaching zero-dose children and missed communities

GROWING MARKET

Demand for the oral cholera vaccine has increased over the past years: in the 15 years between 1997 and 2012, just 1.5 million doses of cholera vaccine were used worldwide; in 2021, approximately 27 million doses were shipped worldwide – a testament to Gavi’s role in increasing supply to meet growing demand.

The issue 

Cholera is an acute intestinal infection caused by contaminated food or water. The disease can quickly lead to severe dehydration and, in its extreme form, can be fatal.

Outbreaks and deaths occur primarily because people cannot access adequate water, sanitation and hygiene (WASH) and treatment, respectively. The majority of cholera cases can be successfully treated with oral rehydration salts, while severe cases require intravenous fluids. Use of oral cholera vaccines in areas known to be high risk for cholera should supplement core prevention efforts to improve water and sanitation.

Routine vaccines: Cholera

Cholera is an acute intestinal infection caused by contaminated food or water. The disease can quickly lead to severe dehydration and, in its extreme form, can be fatal.

Outbreaks and deaths occur primarily because people cannot access adequate water, sanitation and hygiene (WASH) and treatment, respectively. The majority of cholera cases can be successfully treated with oral rehydration salts, while severe cases require intravenous fluids. Use of oral cholera vaccines in areas known to be high risk for cholera should supplement core prevention efforts to improve water and sanitation.

Routine vaccines: Cholera

Gavi’s response 

In 2018, as part of the Vaccine Investment Strategy (VIS), Gavi’s Board approved an investment to expand Gavi’s support for preventive OCV use in high-risk areas, known as "hotspots", while continuing its stockpile support for emergency response. The inclusion of OCV as part of a multisectoral approach to fight cholera was a key achievement during the Gavi 4.0 strategic period (2016–2020), which brought an exponential increase of vaccine use for both for outbreak response and prevention in cholera hotspots.

Due to growing demand from countries around the world and the potential impact of expanding the use of cholera vaccine in known hotspots to prevent outbreaks from starting and spreading, Gavi has recently launched the preventive cholera vaccine programme within its portfolio. Countries can submit multi-year plans for vaccine support beginning in 2023, and are encouraged to include activities related to cholera control in other Gavi funding grants.

Learn more

In 2018, as part of the Vaccine Investment Strategy (VIS), Gavi’s Board approved an investment to expand Gavi’s support for preventive OCV use in high-risk areas, known as "hotspots", while continuing its stockpile support for emergency response. The inclusion of OCV as part of a multisectoral approach to fight cholera was a key achievement during the Gavi 4.0 strategic period (2016–2020), which brought an exponential increase of vaccine use for both for outbreak response and prevention in cholera hotspots.

Due to growing demand from countries around the world and the potential impact of expanding the use of cholera vaccine in known hotspots to prevent outbreaks from starting and spreading, Gavi has recently launched the preventive cholera vaccine programme within its portfolio. Countries can submit multi-year plans for vaccine support beginning in 2023, and are encouraged to include activities related to cholera control in other Gavi funding grants.

Learn more

Latest articles about cholera

24 November 2022

Flood-displaced Nigerians rely on humanitarian intervention to stay healthy as outbreaks threaten

Nigeria's worst flooding in over a decade has left communities in limbo, with residents homeless and at risk of disease. But humanitarian groups are rising to the occasion, distributing life-saving aid from food to mosquito nets, and raising…

23 November 2022

Oral cholera vaccines douse a swelling outbreak in populous Dhaka

After researchers spotted an uptick in patients hospitalised with cholera in the capital city, Bangladesh launched a two-part vaccination campaign to bring the disease to heel.

18 October 2022

Climate change’s impact on healthcare in India

As climate change increases the risk of communicable diseases, India needs a more resilient healthcare infrastructure to counter its impact.

17 August 2022

Cholera vaccine slows down prolonged outbreak in Malawi

Malawi is battling a cholera outbreak in 10 of its 28 districts. Oral cholera vaccines are helping to stem the tide.

21 July 2022

Scientists urge close monitoring of cholera variants

New cholera variants capable of causing large outbreaks could emerge. Constant monitoring is the only way to prevent possible pandemics. World has seen seven pandemics of the infectious disease.

2 June 2022

First came the floods... then came the oral cholera vaccines

Amid massive downpours, southern Laos health workers brace for disease outbreaks.

2 May 2022

Routine vaccines, extraordinary impact: Cholera

The world has been in a cholera pandemic since 1961. Now that the disease is entrenched in so many regions, ensuring access to the vaccine is more important than ever.

27 April 2022

Applying the COVID Blueprint to Cholera

Despite their apparent differences, COVID-19 and cholera have much in common, which explains why measures to limit the former, such as decreased travel and increased attention to personal hygiene, brought about a decline in the latter. It also…

13 April 2022

Stopping cholera before it can start: vaccines reach South Sudan’s flood-hit IDP camps

To pre-empt potential cholera outbreaks due to flooding, Unity State in South Sudan has vaccinated 200,000 people.

13 April 2022

Tackling Cameroon’s worst cholera outbreak in decades

Health experts in Cameroon have called for vigilance and the respect of basic hygienic rules as the country grapples with a severe cholera outbreak.

23 December 2021

Oral Cholera Vaccine saving lives in South Sudan

While South Sudan has been declared cholera-free, it is an ongoing battle to keep things that way.

23 December 2021

Cholera’s 7th Pandemic turns 60

During the six decades of its 7th pandemic, cholera has become an avoidable, survivable scourge. But instead of ebbing away, the disease has emerged more starkly than ever as a vulture of inequity.

23 December 2021

Q&A: “We have the momentum” – fighting to end a 60 year-old cholera pandemic

This year, the ongoing seventh cholera pandemic turned 60. Here, Lorenzo Pezzol, epidemiologist and cholera expert, tells #VaccinesWork that we have the tools to end it – and that we really should have done so long ago.

22 September 2021

Cholera and the inequitable origins of public health diplomacy

The arrival of cholera on European shores in the 19th Century helped kick off the long path towards modern global health institutions and diplomacy. However, these beginnings were anything but fair.

27 August 2021

Fighting both COVID-19 and cholera: Health workers, community leaders work around the clock in Nigeria

With COVID-19 stretching the healthcare system in many parts of Nigeria, health workers and community leaders have to go the extra mile to ensure vaccines reach victims of the country’s latest cholera outbreak.

10 August 2021

John Snow and the Pump Handle of Public Health

The narrative of the Broad Street pump is the story of a vital epidemiological discovery; it’s also a story about discovery: it has the tidy, conclusive quality of a fable about science. But in the years after its discovery, John Snow’s theory of…

Last updated: 19 Jul 2022

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