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New collaboration makes further 100 million doses of COVID-19 vaccine available to low- and middle-income countries
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Collaboration among the Serum Institute of India (SII), Gavi, the Vaccine Alliance and the Bill & Melinda Gates Foundation will accelerate manufacturing and delivery of up to an additional 100 million doses of future vaccines, if proven to be safe and effective, for low- and middle-income countries in 2021
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The expansion follows August’s announcement of up to 100 million doses to be delivered by the collaboration, bringing the total now to be delivered by the partnership to up to 200 million doses of COVID-19 vaccines, priced at a maximum of US$ 3 per dose, with an option to secure more
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Dr Seth Berkley: “This is vaccine manufacturing for the Global South, by the Global South, helping us to ensure no country is left behind when it comes to the race for a COVID-19 vaccine”
Geneva, 29 September 2020 – A further collaboration among the Serum Institute of India (SII), the world’s largest vaccine manufacturer by volume, Gavi and the Bill & Melinda Gates Foundation will accelerate the manufacture and delivery of up to an additional 100 million doses of safe and effective COVID-19 vaccines for low- and middle-income countries (LMICs) as part of the Gavi COVAX AMC, a mechanism within the COVAX Facility.
This brings the total number of vaccine doses to be covered by the partnership between SII, Gavi, and the Gates Foundation to an aggregate of up to 200 million doses, following the initial agreement announced in August. This arrangement again provides an option to secure additional doses, potentially several times the 200 million dose total, if the COVAX Facility sees a need for it.
The collaboration will provide upfront capital to SII to help it increase manufacturing capacity now so that, once a vaccine, or vaccines, gains regulatory approval and WHO Prequalification, doses can be distributed at scale to LMICs as part of the Gavi COVAX AMC mechanism as early as the first half of 2021.
“This is vaccine manufacturing for the Global South, by the Global South, helping us to ensure no country is left behind when it comes to access to a COVID-19 vaccine,” said Dr Seth Berkley, CEO of Gavi, the Vaccine Alliance. “The momentum behind our effort to ensure global, equitable access to COVID-19 vaccines is really building. Last week we were able to announce the historic number of countries that are now signed up to the COVAX Facility, today we can announce further doses of safe, effective vaccines that will be reserved specifically for low- and middle-income countries. No country, rich or poor, should be left at the back of the queue when it comes to COVID-19 vaccines; this collaboration brings us another step closer to achieving this goal.”
The funding will help accelerate the manufacturing by SII for candidate vaccines licensed from AstraZeneca and Novavax, which will be available for procurement if they are successful in attaining full licensure and WHO Prequalification. The vaccines will have a ceiling price of US$3 per dose, a price enabled by investments made by partners such as the Coalition for Epidemic Preparedness Innovations (CEPI), the Bill & Melinda Gates Foundation and SII.
“The collaboration further bolsters our fight against COVID-19! Through the avid support of Gavi and the Bill & Melinda Gates Foundation, we will now manufacture and deliver up to an additional 100 million doses of immunogenic and safe-proven future COVID-19 vaccines to India and low- and middle-income countries in 2021,” said Adar Poonawalla, CEO of Serum Institute of India “At this stage, It is important for governments, global health and financial institutions in the public and private sector to come together in ensuring that no one is left behind in the road to recovery. This association is in line with our efforts to see that future vaccines reach the remotest parts of the world providing full immunization coverage in a bid to contain the spread of the pandemic.”
The Gavi COVAX AMC, which is currently seeking at least US$2 billion in initial seed funding, will meet at least part of the cost of procurement for the vaccine doses. The Gavi Board has agreed upon the final list of 92 countries that will be supported by the Gavi COVAX AMC. Under the new collaboration, AstraZeneca’s candidate vaccine, if successful, will be available to 61 AMC-eligible countries. Novavax’s candidate, if successful, will be available to all 92 countries supported by the Gavi COVAX AMC. These countries align with SII’s licensing agreements with the two partners.
“This collaborative effort shows the capacity of the Access to COVID-19 Tools (ACT) Accelerator to bring together diverse partners to ensure a fair and effective response to this global crisis,” said Mark Suzman, CEO of the Bill & Melinda Gates Foundation.
The collaboration between Gavi, SII, and the Gates Foundation supports the efforts of the ACT Accelerator's vaccines pillar, also known as COVAX, co-led by Gavi, CEPI and the World Health Organization (WHO), to accelerate the development of COVID-19 vaccines and ensure rapid, global access to them. Decisions around investment in manufacturing are taken in close collaboration between these three lead organisations of the COVAX pillar.
Under the COVAX umbrella, Gavi is coordinating the COVAX Facility, which provides governments with the opportunity to benefit from a large portfolio of COVID-19 candidate vaccines using a range of technology platforms, produced by more manufacturers across the world, with a bigger market to provide security of demand.
So far 75 higher-income economies have formally committed to join the Facility, in addition to the 92 low- and middle-income economies that are eligible for support from the Gavi COVAX AMC.
The Bill & Melinda Gates Foundation, via its Strategic Investment Fund, will provide at-risk funding of a further US$150 million to Gavi, bringing the total funding provided through this collaboration to US$300 million. This will be used to support the Serum Institute of India to manufacture potential vaccine candidates, and for future procurement of vaccines for low- and middle-income countries via Gavi’s COVAX AMC.
The deal is additional to a Memorandum of Understanding between AstraZeneca and Gavi, announced in June, which will commit an additional 300 million doses of AstraZeneca’s candidate vaccine to the wider COVAX Facility, to be supplied upon licensure or prequalification. These two deals can help assure access to early doses for the most vulnerable on a truly global scale.
Media Contacts
James Fulker, Gavi
Phone: +41 79 429 55 05
Email: jfulker@gavi.org
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As part of Gavi’s work supporting lower-income countries’ response to COVID-19, the Alliance is providing US$ 40 million to UNICEF to secure supplies of personal protective equipment (PPE) and diagnostics for 58 countries.
Gavi and global health actors collaborate to accelerate COVID-19 technologies for all
Goal of new global collaboration is to make COVID-19 diagnostics, therapeutics and vaccines available to everybody that needs them as quickly as possible.
Saudi Arabia pledges US$ 150 million to Gavi COVID response
Pledge follows G20 commitment to provide immediate resources to Gavi.
Reed Hastings and Patty Quillin support Gavi with US$ 30 million donation
Cash donation supports the Alliance’s response to COVID-19 and helps protect the world against new outbreaks of other infectious diseases.
COVID-19: massive impact on lower-income countries threatens more disease outbreaks
At least 13.5 million people to miss out on vaccinations due to postponement of campaigns and interruptions in routine vaccinations, with millions more likely to follow.
With senior health officials setting the annual direction for the World Health Organization this week, multiple health challenges and considerations vie for attention amidst a packed agenda. Find out how Gavi helps ensure that immunisation is…
Study: vaccines prevent not just disease, but also poverty
New study shows that immunisation in the world’s poorest countries is set to save millions from one of the primary causes of extreme poverty: health expenses
Ebola vaccine purchasing commitment from Gavi to prepare for future outbreaks
Agreement will help push vaccine towards regulatory approval.
World leaders make record-breaking commitment to protect poorest children with vaccines
Support puts Gavi, the Vaccine Alliance on the path to immunise a further 300 million children and save up to 6 million more lives.
Gavi commits to purchasing Ebola vaccine for affected countries
Vaccine Alliance ready to begin procurement as soon as WHO recommends a vaccine for use.
Five nations and the Bill and Melinda Gates Foundation launch Advance Market Commitment for vaccines
With an additional US $1 billion per year immunization could save ten million more lives in a decade
Prime Minister of India calls on world leaders to embrace vaccines as key to saving children's lives