Gavi’s market shaping efforts aim to make life-saving vaccines and other immunisation products more accessible and affordable for lower-income countries.
Healthy markets for vaccines and other immunisation products allow manufacturers to plan production based on known demand, donors to maximise their investments and, most importantly, lower- and middle-income countries to buy suitable products at prices they can afford.
Market failures
Market forces do not always serve low-income countries well. Historically, uncertain funding and demand for vaccines led to manufacturers not having the incentive to invest in new products at affordable prices for developing countries.
As a result, there was often a long time lag between the time a vaccine was available in rich countries and when it was introduced in LMICs.
One of the core drivers for Gavi’s founding in 2000 was the need to address these market failures. Gavi’s fourth strategic goal, specific to shaping markets, seeks to further Gavi’s vision of “Leaving no one behind with immunisation”, and to establish functioning markets that will serve countries far into the future.
Priorities
The market shaping strategy has three priorities:
- Optimise vaccine programme affordability to countries and Gavi;
- Maintain supply access, security and market heath; and
- Develop future markets for Vaccine Investment Strategy (VIS)-endorsed and outbreak, epidemic and pandemic (OEP) vaccines.
The healthy markets framework
In 2015, the Gavi Secretariat, UNICEF, and the Gates Foundation jointly developed a healthy markets framework (HMF).
The framework helps us to develop common strategies for vaccine markets across the Vaccine Alliance through the development of a clear and consistent definition of market health. Its main aims include: establishing a common way of thinking about market health, communicating Alliance assessments of individual markets, and improving trade-offs between how different market elements are analysed.
The HMF has consistently evolved with each Market shaping strategy to adapt to the realities of each strategic period. For the 2021–2025 strategic period (Gavi 5.0), the HMF was redesigned to take demand health into account, reflect a greater emphasis on long-term market views, and add a new dimension on regional diversification across suppliers. The 2026–2030 (Gavi 6.0) version includes a more concrete and quantifiable definition of supply security to support a structured evaluation of the Alliance’s risk appetite for supply security and associated trade-offs.
- More information on the HMF can be found here.
Regional manufacturing strategy
Our regional manufacturing strategy (RMS) was developed to respond to the challenge surrounding equitable access to vaccines during the COVID-19 pandemic, and to the African Union’s call to action on building regional manufacturing capacity in Africa. This includes the African Vaccine Manufacturing Accelerator (AVMA), a financing mechanism established to accelerate the expansion of commercially viable vaccine manufacturing in Africa.

Vaccine demand forecasting
Long-term strategic demand scenarios offer visibility into future market needs to Gavi stakeholders.

Market shaping roadmaps
Market shaping roadmaps help guide Gavi’s market shaping efforts by analysing the dynamics of each vaccine or other immunisation product market.

Product information for vaccines and cold chain equipment
Detailed product profiles and the Cold Chain Equipment Technology Guide help countries decide which vaccine presentations or cold chain equipment are the best “fit” for their immunisation programmes.

The Vaccine Innovation Prioritisation Strategy
VIPS represents an unprecedented three-year collaboration between the Gavi Secretariat, World Health Organization (WHO), Gates Foundation (GF), United Nations Children’s Fund (UNICEF) and PATH – known as the VIPS Alliance – to develop a single integrated framework to evaluate and prioritise vaccine product innovations and to drive these innovations forward.